Preclinical in vitro and in vivo studies have demonstrated the potency of SPR720 against clinically important mycobacteria, including NTM species Mycobacterium avium complex and Mycobacterium abscessus
. In June 2019, SPR720 was the focus of an equity investment by the Novo REPAIR Impact Fund for up to $10 million.
Septic arthritis caused by Mycobacterium fortuitum and Mycobacterium abscessus
in a prosthetic knee joint: case report and review of literature.
Most notably was the outbreak in Anaheim, California, where 72 healthy children, ages 2-12, were infected with mycobacterium abscessus
, a similar bacteria to those causing tuberculosis and leprosy.
It is less common for an antibiotic-resistant gene to be identified as a diagnostic antigen with high specificity; however, it has been found that a high similarity homolog of the erm family is mainly restricted to the tuberculosis complex and limited species of Mycobacterium, including Mycobacterium abscessus
and Mycobacterium bolletii.
infections among patients of a pediatric dentistry practice--Georgia, 2015.
Extensive cutaneous Mycobacterium abscessus
infection due to contaminated insulin delivery system.
In vitro evaluation of a new drug combination against clinical isolates belonging to the Mycobacterium abscessus
However, he developed a systemic infection with Mycobacterium abscessus
El complejo Mycobacterium abscessus
pertenece a las micobacterias de crecimiento rapido (MCR) que se encuentran ampliamente distribuidas en el suelo y en el agua.
Culture grew Mycobacterium abscessus
which was sensitive to amikacin, linezolid and clarithromycin.
The company has received the grant to study the treatment of two pulmonary non-tuberculous mycobacteria infections - Mycobacterium avium and Mycobacterium abscessus
- with the company's inhaled Linhaliq and Lipoquin products.