PTEN(redirected from Mutated in Multiple Advanced Cancers 1)
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PTENA gene on chromosome 10q23.3 which encodes PTEN (phosphatase and tensin homolog), a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase protein, which acts as a tumour suppressor by negatively regulating the AKT/PKB-signalling pathway.
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