site-directed mutagenesis(redirected from Mutagenesis, site-directed)
the controlled alterations of selected regions of a DNA molecule.
Farlex Partner Medical Dictionary © Farlex 2012
site-directed mutagenesisAn experimental technique in which a mutation is inserted in DNA at a particular site to determine the site’s function, if any. In site-directed mutagenesis, nucleotides are altered, resulting in substitution of amino acids in a protein of known function, which serves to identify the DNA sequence’s role (e.g., as a receptor or ion channel).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.