mustine

mechlorethamine

A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.

Global village
Mechlorethamine was first developed as a chemical weapon.

Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
 
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

mustine

Chlormethine, a drug used to treat some cases of HODGKIN'S DISEASE. It is very toxic and is liable to cause severe vomiting.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Long term follow up of topical mustine treatment for cutaneous langerhans cell histiocytosis.
Kasich, Solon Vice Mayor Edward Kraus and Jobs Ohio Managing Director David Mustine.
"Recycling saves energy, conserves our natural resources, and extends the life of a landfill, all while creating jobs," said David Mustine, Director of the Ohio DNR.
(15,19) When treatment is necessary, a minimalist approach should be selected--one that includes a topical steroid, topical mustine (nitrogen mustard, an alkylating agent), and possibly steroid injections.