A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.

Global village
Mechlorethamine was first developed as a chemical weapon.

A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Chlormethine, a drug used to treat some cases of HODGKIN'S DISEASE. It is very toxic and is liable to cause severe vomiting.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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