muscarinic

(redirected from Muscarinic acetylcholine receptor)
Also found in: Dictionary, Acronyms, Wikipedia.

mus·ca·rin·ic

(mŭs'kă-rin'ik),
1. Having a muscarinelike action, that is, producing effects that resemble postganglionic parasympathetic stimulation.
See also: muscarine, nicotinic.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic.

mus·ca·rin·ic

(mŭs'kă-rin'ik)
1. Having a muscarinelike action, i.e., producing effects that resemble postganglionic parasympathetic stimulation.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic

muscarinic

1. Producing the effects of post-ganglionic cholinergic stimulation of the parasympathetic. Having an effect similar to that of the mushroom poison MUSCARINE.
2. Of an acetylcholine receptor that responds to muscarine. Compare NICOTINIC.

muscarinic

(in physiological terminology) having acetylcholine receptors that are sensitive to muscarine but not to nicotine.
References in periodicals archive ?
Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice.
(1986) Reconstitution of the muscarinic acetylcholine receptor. Guanine nucleotide-sensitive high affinity binding of agonists to purified muscarinic receptors reconstituted with GTP-binding proteins (Gi and Go).
Wakamatsu et al., "New epitopes and function of anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjoogren's syndrome," Clinical and Experimental Immunology, vol.
The sequences of primers were used in the polymerase chain reaction (PCR) using synthetic primers specific to choline acetyltransferase (ChAT), acetylcholine esterase (AChE), muscarinic acetylcholine receptors (Mj mAChR and [M.sub.2] mAChR), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as follows:
For instance, muscarinic acetylcholine receptor M2 (CHRM2), neuronal acetylcholine receptor subunit [alpha]-2 (CHRNA2), gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3), NO synthase, inducible (NOS2), cGMP-inhibited 3'?,5'-cyclic phosphodiesterase A (PDE3A), and sodium-dependent dopamine transporter (SLC6A3) recorded beyond average mRNA expression in all six groups.
The muscarinic acetylcholine receptor antagonist atropine (10-100 [micro]M) did not change the sensitivity of sea urchin larvae to chlorpyrifos (experiments on S.
Muscarinic Acetylcholine Receptors. Muscarinic acetylcholine (ACh) receptors belong to the GPCR family and consist of five distinct receptor subtypes (M1 to M5).
Cellular signaling mechanisms for muscarinic acetylcholine receptors. Receptors Channels.
Ishikawa, "Muscarinic acetylcholine receptors on human lymphocytes in patients with Meniere's disease," Acta Oto-Laryngologica, vol.
When there is expression of Muscarinic overstimulation due to excess acetylcholine at Muscarinic acetylcholine receptors symptoms of visual disturbances, tightness in chest, wheezing due to bronchoconstriction, increased bronchial secretions, increased salivation, lacrimation, sweating, peristalsis, and urination can occur.
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.