Murray Valley encephalitis


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Related to Murray Valley encephalitis: Japanese Encephalitis, Kunjin virus

Mur·ray Val·ley en·ceph·a·li·tis

a severe encephalitis with a high mortality rate occurring in the Murray Valley of Australia; the disease is most severe in children and is characterized by headache, fever, malaise, drowsiness or convulsions, and rigidity of the neck; extensive brain damage may result; it is caused by the Murray Valley encephalitis virus (genus Flavivirus).

Murray Valley encephalitis

A rare, Japanese encephalitis-like disease caused by a flavivirus-group B togavirus, which occurs in small epidemic clusters in Murray Valley and elsewhere in Victoria and New South Wales, Australia. It is maintained by a cycle between wild birds and mosquitoes (Culex annulirostris), and is favoured by hot weather.
 
Clinical findings
Usually asymptomatic; if symptomatic, fever, headache, nausea, vomiting, loss of appetite, diarrhoea, muscle aches. Neurological changes, if present, include severe headache, neck stiffness, photophobia, drowsiness and confusion. Rare cases may be characterised by co-ordination and speech defects, seizures, loss of consciousness, coma and death; the latter cases may have residual neurologic dysfunction.

Mur·ray Val·ley en·ceph·a·li·tis

(mŭr'ē val'ē en-sef'ă-līt'is)
A severe encephalitis with a high mortality rate occurring in the Murray Valley of Australia; the disease is most severe in children and is characterized by headache, fever, malaise, drowsiness or convulsions, and rigidity of the neck; extensive brain damage may result; it is caused by the Murray Valley encephalitis virus (genus Flavivirus).
Synonym(s): Australian X disease.

Murray Valley,

location in Australia where epidemics occurred in 1950 and 1951.
Murray Valley disease - Synonym(s): Murray Valley encephalitis
Murray Valley encephalitis - a severe encephalitis with high mortality. Synonym(s): Australian X disease; Australian X encephalitis; Murray Valley disease
Murray Valley virus - a group B arbovirus that causes Murray Valley encephalitis. Synonym(s): Australian X disease virus; MVE virus
References in periodicals archive ?
Acute encephalitis has heralded the emergence of multiple virulent pathogens (28), including West Nile virus, Hendra virus, Nipah virus, Murray Valley encephalitis virus, and Japanese encephalitis virus, all of which can cause severe illness and death (2,4,29-31).
Usutu virus (USUV) is a relatively unknown member of the mosquito-borne cluster within the Flavivirus genus, closely related to important human pathogens such as Japanese encephalitis virus (JEV), Murray Valley encephalitis virus (MVEV), Dengue virus (DENV), Yellow fever virus (YFV), Saint Louis encephalitis virus (SLEV), and West Nile virus (WNV) (1-3).
The causative agent, West Nile virus (WNV), is a member of the genus Flavivirus (family Flaviviridae), which is grouped together with Alfuy virus, Cacipacore virus, Koutango virus, Japanese encephalitis virus, Kunjin virus, Murray Valley encephalitis virus, St.
Monoclonal antibodies used for characterization of goose, stork, and gull isolates study, Israel, 1998 and 1999 MAb Reactivity Reference 2B4 WNV-type specific (E gene) 15 6B8 WNV-type specific (E gene) 15 6E12 WNV-type specific except KUN 15 (NS4a gene) 5F10 WNV specific Bat-El Lachmi 1C9 Flaviviruses Bat-El Lachmi 1B4 Flaviviruses Bat-El Lachmi F7/101 West Nile 16 6D12 Flaviviruses except Edge Hill and 17 Dengue virus 3H6 Murray Valley encephalitis virus 17 (Flavivirus) 813 Yellow fever virus (Flavivirus) 18 30.11 SINV 19 30.12 SINV 19 2F2 SINV (a) WNV= West Nile virus; SINV=Sindbis virus.

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