antibiotic resistance

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antibiotic resistance

Infectious disease The relative or complete ability of an organism–bacterium, fungus to counteract the desired bacteriocidal or bacteriostatic effect of one or more antimicrobial agents

antibiotic resistance

The natural tendency for bacteria, under the processes of natural selection in an antibiotic-rich environment, to evolve in such a way as to become capable of surviving in spite of these drugs. Antibiotic resistance is a rapidly increasing problem largely as a result of worldwide misuse and overuse of antibiotics in conditions that do not require them. See also ANTIBIOTIC-RESISTANT STAPHYLOCOCCI.

Patient discussion about antibiotic resistance

Q. Are superbugs contagious through the air? Last week we visited my dad in the hospital, and we noticed that on the next room’s door there was a warning sign. After asking, we were told it was a denoting that the patient inside had a superbug (called klebsiella). On our way out we passed against this patient in the hallway – is it possible that I also carry this superbag? Is it dangerous?

A. Usually these bacteria are transmitted from person to person through direct contact, and less through the air. Moreover, these germs are dangerous in ill and debilitated patients, and not in normal healthy individuals.

Q. Why Is it Important to Not Use Antibiotics Often? Why is my doctor always so reluctant to prescribe me antibiotics?

A. Antibiotic resistance has become a serious problem in both developed and underdeveloped nations. By 1984 half of those with active tuberculosis in the United States had a strain that resisted at least one antibiotic. In certain settings, such as hospitals and some childcare locations, the rate of antibiotic resistance is so high that the usual, low-cost antibiotics are virtually useless for treatment of frequently seen infections. This leads to more frequent use of newer and more expensive compounds, which in turn leads to the rise of resistance to those drugs. A struggle to develop new antibiotics ensues to prevent losing future battles against infection. Therefore the doctors try to avoid using antibiotics when it is not necessary, and try to keep a certain limited use of these medications.

More discussions about antibiotic resistance
References in periodicals archive ?
Late-onset VAPs are associated with predisposing factors such as hospitalization time, use of mechanical ventilator and previous use of antimicrobials, having as etiological agents, more frequently, multiresistant bacteria such as ORSA [15,28,29].
To the Editor: Unusual and multiresistant bacterial infections are increasingly reported in cystic fibrosis (CF) patients (1).
In addition, previous hospitalization is a risk factor for acquiring multiresistant uropathogens (from the hospital environment) (16).
A multiresistant SCCmec type III and coagulase type 36 genotype, and a non-multiresistant SCCmec type IV with different genetic backgrounds of MRSA were identified in Bahrain.
The six-year prevalence of carbapenem-resistant Pseudomonas aeruginosa (CRPA), Klebsiella pneumonia (CRKP), multiresistant Escherichia coli (MREC), and Methicillin-resistant Staphylococcus aureus (MRSA) was determined based on data published by the European Centre for Disease Prevention and Control (ECDC)
This discovery will help researchers develop new drugs to treat multiresistant bacteria.
aureus infections in recent years in Brazil, these results seem to be related with MRSA clonal lineages dissemination in this institution, reinforcing that surveillance and spread control of multiresistant bacteria should be continuously monitored in health institutions worldwide.
The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool.
In the last few months, from June 2018, onwards, there have been upsurge of multiresistant enteric infections in children admitted from various catchment areas of Abbasi Shaheed Hospital (ASH) to the paediatric ward unit 2, of ASH, with no response to cephalosporins.
These infections, often caused by multiresistant pathogens, take a heavy toll on patients and their families by causing illness, prolonged hospital stay, potential disability, excess costs and sometimes death.The infections are transmitted through direct contact with the body or indirect contact through contaminated instruments, needles, dressings, contaminated and unwashed hands, or gloves that are not changed between patients.
Multiresistant Acinetobacter baumannii infections: epidemiology and management.