mucosa-associated lymphoid tissue


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Related to mucosa-associated lymphoid tissue: cell-mediated immunity

mucosa-associated lymphoid tissue (MALT),

a class of lymphoid tissue comprising nodular aggregates found in association with the wet mucosal surfaces of the body such as those of the respiratory, digestive, and urinary systems.

MALT

Mucosa-associated lymphoid tissue. An umbrella term for extranodal aggregates of lymphoid tissue in the bronchus (BALT), gut (GALT) and skin (SALT), as well as breast and uterine cervix. MALT is the arm of the immune defence in closest contact with exogenous antigens, thus differing from the compartmentalised peripheral somatic lymphoid tissues, which include the lymph nodes, thymus and spleen. Dimeric IgA or “secretory” IgA appears to be under MALT’s control, and MALT may be the sites of origin of extranodal lymphomas.

mu·co·sa-as·so·ci·a·ted lym·phoid tis·sue

(MALT) (myū-kō'să-ă-sō'sē-ā-tĕd lim'foyd tish'ū)
A class of lymphoid tissue comprising nodular aggregates found in association with the wet mucosal surfaces of the body such as those of the respiratory, digestive, and urinary systems.

mucosa-associated lymphoid tissue

Abbreviation: MALT
Aggregates of T and B lymphocytes found in all mucous membranes, a line of defense against infection. Examples include Peyer's patches in the small intestine and lymph nodules in the colon, trachea, and bronchi. MALT contains CD4+ and CD8+ T cells and activated B cells and may occasionally undergo malignant transformation into lymphomas.
See: mucosal immune system
See also: tissue
References in periodicals archive ?
Itoh et al., "Primary low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT)-type of the liver in a patient with hepatitis C virus infection," Leukemia & Lymphoma, vol.
Mauch, "Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma," Annals of Oncology, vol.
(iv) Histologic features of mucosa-associated lymphoid tissue lymphoma with centrocyte-like cells, plasmacytoid occurred.
C Wotherspoon, "Helicobacter pylori infection in gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma: a re-evaluation," Gut, vol.
Deng et al., "Concurrent colonic mucosa-associated lymphoid tissue lymphoma and adenoma diagnosed after a positive fecal occult blood test: a case report," Journal of Medical Case Reports, vol.
pylori is involved in the development of several gastroduodenal diseases, including gastritis, peptic ulcer disease, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue lymphoma and its eradication could change the natural history of some of these.3 Second, both patient compliance and antibiotic resistance have a major negative impact on the efficacy of the recommended therapies and this can lead to unacceptable results.
Primary renal lymphoma (PRL) is rare, and most are intermediate- and high-grade lymphomas of B-cell lineage, such as diffuse large B-cell or Burkitt lymphoma.[sup.1] Low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) arising from the kidney is extremely rare.
Primary lymphoma of the stomach is extremely rare in childhood, and is frequently designated as mucosa-associated lymphoid tissue (MALT) lymphoma in adults (5).
Findings on pathologic examination were consistent with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma).
Other indications include peptic ulcer disease, nonulcer dyspepsia, mucosa-associated lymphoid tissue (MALT) lymphoma, atrophic gastritis, a history of gastric cancer resection, first-degree relatives of patients with gastric cancer, and patients who, on consulting with a physician, want to be tested.
Primary low-grade B-cell lymphoma of mucosa-associated lymphoid tissue of the dura mimicking the presentation of an acute subdural hematoma.
pylori eradication prevents the development (21) and recurrence (22) of gastric carcinoma and promotes regression of B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) tissue of the stomach (23), the proposed test-and-treat strategy may be an efficient use of health resources in Kenya and perhaps other African countries.