Sly syndrome

(redirected from Mucopolysaccharidosis type VII Sly syndrome)

Sly syn·drome

an autosomal recessive disorder due to a deficiency of a β-glucuronidase; defective lysosomal degradation of dermatan sulfate, heparan sulfate, and chondroitin sulfate; cellular function disrupted in most tissues.

Sly syn·drome

an autosomal recessive disorder due to a deficiency of a β-glucuronidase; defective lysosomal degradation of dermatan sulfate, heparan sulfate, and chondroitin sulfate; cellular function disrupted in most tissues.

Sly syndrome

(slī)
n.
A type of mucopolysaccharidosis (MPS VII) characterized by the presence of dermatan sulfate, heparan sulfate, and chondroitin sulfate in the urine, corneal clouding, enlargement of the liver and spleen, skeletal abnormalities, and sometimes intellectual disability.

Sly,

William S., U.S. pediatrician, 1932–.
Sly syndrome - beta-glucuronidase deficiency that causes short stature with hepatosplenomegaly and frequent pulmonary infections; may also cause slow development, coarse facies, and clouded corneas. Synonym(s): type VII mucopolysaccharidosis
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