Muckle-Wells syndrome

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Muck·le-Wells syn·drome

(muk'ĕl welz), [MIM*191900]
a syndrome characterized by amyloidosis, notably involving the kidneys, progressive sensorineural hearing loss, and periods of febrile urticaria associated with pain in joints and muscles of the extremities; autosomal dominant inheritance.


Thomas James, 20th century Canadian pediatrician.
Muckle-Wells syndrome - a syndrome characterized by familial amyloidosis.


Michael Vernon, 20th century English physician.
Muckle-Wells syndrome - see under Muckle
References in periodicals archive ?
Muckle-Wells syndrome without mutation in exon 3 of the NLRP3 gene, identified by evidence of excessive monocyte production of functional interleukin 1[sz] and rapid response to anakinra.
Muckle-Wells syndrome is more severe; patients also may haw sensorineural hearing loss, conjunctivitis, retinitis, arthritis, periodic fevers, abdominal pain, and amyloidosis.