guaifenesin

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Related to Mucinex: guaifenesin

expectorant

 [ek-spek´to-rant]
1. promoting expectoration.
2. an agent that so acts.
liquefying expectorant an expectorant that promotes the ejection of mucus from the respiratory tract by decreasing its viscosity.

guaifenesin (glyceryl guaiacolate)

Balminil Expectorant (CA), Benilyn Childrens Chesty Coughs (UK), Benylin-E (CA), Calmylin Expectorant (CA), Diabetic Tussin EX, Genatuss, Koffex Expectorant (CA), Mucinex, Organidin NR, Phanacin XPECT, Pneumomist, Resyl (CA), Robitussin, Robitussin Chesty Cough (UK), Scot-tussin Expectorant, Siltussin SA, Tixylix Chesty Cough (UK), Venos for Kids (UK), Vicks Vaposyrup for Chesty Coughs (UK)

Pharmacologic class: Propanediol derivative

Therapeutic class: Expectorant

Pregnancy risk category C

Action

Exerts vasoconstrictive action that leads to decreased edema and congestion. Also increases respiratory secretions and reduces mucus viscosity.

Availability

Capsules: 200 mg

Oral solution: 100 mg/5 ml, 200 mg/5 ml

Syrup: 100 mg/5 ml

Tablets: 100 mg, 200 mg, 400 mg

Tablets (extended-release): 600 mg

Indications and dosages

Cough due to upper respiratory tract infection

Adults: 200 to 400 mg P.O. q 4 hours (not to exceed 2,400 mg/day), or 600 to 1,200 mg P.O. (extended-release tablets) q 12 hours (not to exceed 2,400 mg/day)

Children ages 6 to 12: 100 to 200 mg P.O. q 4 hours (not to exceed 1,200 mg/day), or 600 mg P.O. (extended-release) q 12 hours (not to exceed 1,200 mg/day)

Children ages 2 to 6: 50 to 100 mg P.O. q 4 hours (not to exceed 600 mg/day)

Contraindications

• Hypersensitivity to drug

• Alcohol intolerance (with some products)

Precautions

Use cautiously in:

• diabetes mellitus, cough lasting more than 1 week or accompanied by fever, rash, or headache

• patients receiving disulfiram concurrently

• pregnant patients.

Administration

• Give with full glass of water.

Adverse reactions

CNS: headache, dizziness

GI: nausea, vomiting, diarrhea, stomach pain

Skin: rash, urticaria

Interactions

Drug-diagnostic tests. Urinary 5-hydroxyindoleacetic acid, vanillylmandelic acid: inaccurate results

Patient monitoring

• Assess cough quality and productivity. Reevaluate treatment if cough persists and is accompanied by fever or headache.

Patient teaching

• Tell patient to take with 8 oz of water and to drink plenty of fluids.

• Instruct patient to contact prescriber if cough lasts more than 1 week.

• Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.

• As appropriate, review all other significant adverse reactions and interactions, especially those related to the tests mentioned above.

guai·fen·e·sin

(gwī-fen'ĕ-sin),
An expectorant that allegedly reduces the viscosity of sputum, thus facilitating its elimination.

guaifenesin

(gwī-fĕn′ə-sĭn)
n.
An expectorant drug, C10H14O4, that is used to thin mucus and sputum.

guaifenesin

Monafed® Common cold An OTC agent for relief of cold/cough. See Common cold.

guai·fen·e·sin

(gwī-fen'ĕ-sin)
An expectorant that allegedly reduces the viscosity of sputum, thus facilitating its elimination.

guai·fen·e·sin

(gwī-fen'ĕ-sin)
An expectorant that allegedly reduces viscosity of sputum, thus facilitating its elimination.
References in periodicals archive ?
(BSE: 500124) (NSE: DRREDDY) (NYSE: RDY) has launched an over-the-counter store-brand equivalent of Mucinex D Extended Release Tablets in two strengths, Guaifenesin 600 mg and Pseudoephedrine HCl 60 mg, and Guaifenesin 1200 mg and Pseudoephedrine HCl 120 mg, in the United States market, as approved by the US Food and Drug Administration (USFDA), the company said.
Mucinex Fast Max Clear & Cool 682 - 17.9% 17.66
Find out more health tips on how to combat the common cold at Mucinex.com.
Healthcare company Perrigo Company plc (NYSE:PRGO)(TASE:PRGO) reported on Wednesday the receipt of final approval from the US Food & Drug administration for the store brand OTC equivalent of Mucinex DM Maximum Strength (Guaifenesin and Dextromethorphan Hydrobromide Extended-Release Tablets, 1200 mg/60 mg).
Adams filed the lawsuit in response to Perrigo's notification that it filed a Paragraph IV Certification in connection with its Abbreviated New Drug Application (ANDA), which seeks FDA approval to engage in the commercial manufacture, use or sale of guaifenesin 600 mg single-ingredient, extended-release tablets (equivalent to Adams' Mucinex SE), prior to the expiration of the '252 patent.
Mucinex tablets are a good choice if you are having thick phlegm; consider Mucinex DM for thick phlegm accompanied by persistent coughing.
M2 PHARMA-March 8, 2018-Perrigo reports US FDA approval & upcoming launch of store brand cough control equivalent of Mucinex DM Maximum Strength
and Mucinex reveals that about 13.9 million Americans will call in sick Monday following Super Bowl LII, which will make it one of the biggest sick days of the year.
M2 EQUITYBITES-May 4, 2016-Perrigo & Allergan partnership unveils store brand OTC equivalent to Mucinex 1200mg DM extended-release tablets
A strong period for heartburn relief Gaviscon was offset by weak sales of decongestant Mucinex, Strepsils lozenges and some products in the Nurofen range due to "lower incidence" of colds and flu.
The FDA approved over-the-counter Mucinex D Extended-Release Tablets for adults and children 12 years and older.
* Mucinex D (guaifenesin/pseudoephedrine HCI, Adams Laboratories Inc.)