MMTV

(redirected from Mouse mammary tumour virus)

MMTV

Mouse mammary tumour virus. A group-B oncovirus, the genome of which is integrated in the mouse genome.
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The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.
Similarly mouse mammary tumour virus (MMTV) has been found to cause breast cancer in mice, and it has been shown that the virus could infect breast cells in humans (Retrovirology, DOI:10.1186/1742-4690, vol.4,p 73).

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