Jansen et al.," Immunohistochemical characterization of mossy fibre
sprouting in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy," Brain, vol.
Sakmann, "Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus," The Journal of Physiology, vol.
Yamamoto, "Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses," Journal of Physiology, vol.
(1982) Climbing fibre induced depression of both mossy fibre
responsiveness and glutamate sensitivity of cerebellar Purkinje cells.
These tools will be used here to test hypotheses regarding functions of KARs in granule cells (GCs) in the dentate gyrus of the hippocampal formation, with a focus on mossy fibre
long-term potentiation (LTP).
Nicoll, "Presynaptic changes during mossy fibre
LTP revealed by NMDA receptor-mediated synaptic responses," Nature, vol.
Tongroach, "Climbing fibre induced depression of both mossy fibre
responsiveness and glutamate sensitivity of cerebellar Purkinje cells, " Journal of Physiology, vol.
Text book descriptions of the cerebellum tell us there are two types of input to the cerebellum: mossy fibres
and climbing fibres.
When the team followed the structural changes in the hippocampus during the conditioning process, they found a large increase in the numbers of synaptic structures at the terminals of neurons called granule cells, which have axons called large mossy fibres
after the memories were formed.
represent a major intrahippocampal associative pathway.