monokine

(redirected from Monokines)
Also found in: Dictionary, Encyclopedia.
Related to Monokines: Cytokines, Lymphokines

monokine

 [mon´o-kīn]
any of various soluble mediators of immune responses that are not antibodies or complement components and that are produced by mononuclear phagocytes (monocytes or macrophages).

mon·o·kine

(mon'ō-kīn),
Cytokines secreted by both monocytes and macrophages. These substances influence the activity of other cells. See: cytokine.
[monocyte + G. kineō, to set in motion]
References in periodicals archive ?
CXCL9/Mig, a monokine induced by interferon- (IFN-) gamma induced protein 1 (IP-10), is a type 1 C-X-C chemokine and displays strong chemoattraction for T-helper type 1 (Th 1) lymphocytes [57, 58].
Table 2-3 Some Types of Cytokines and Their Functions Type Source Function Interleukin-1 Monokine produced by Activates B and activated macrophages T lymphocytes; mediates inflammation Interleukin-2 Lymphokine produced by Growth factor for B and helper T cells T lymphocytes; enhances cytotoxic effects of nonkiller (NK) cells Interferon Lymphokine produced by Activates macrophages; helper and suppressor promotes B- and T-cell T cells differentiation; activates neutrophils and NK cells Tumor necrosis Monokine produced by Mediator of inflammation factor activated macrophages Table 2-4 Phases of Acquired Immunity Phase Action Recognition Exposure to a specific antigen resulting in selective activation and expansion of those lymphocytes with antigenic receptors specific for that antigen.
Cytokines--Include lymphokines, monokines, and other polypeptides that regulate immunologic, inflammatory, and reparative host responses.
Production of monokines in patients under polysulphone haemodiafiltration is influenced by the ultrafiltration flow rate.
Machophage function in alloxan diabetic mice: expression of cadhesion mollecules, generation of monokines and oxygen and NO radicals.
Interactions of immunoreactive monokines (interleukine-1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis.
Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells.