monocyte chemoattractant protein

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monocyte chemoattractant protein

a cytokine involved in monocyte migration.

mo·no·cyte che·mo·at·trac·tant pro·tein

(mon'ō-sīt kē'mō-ă-trak'tănt prō'tēn)
A cytokine involved in monocyte migration.
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Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease.
Monocyte chemoattractant protein (MCP-1) is expressed in human cardiac cells and is differentially regulated by inflammatory mediators and hypoxia.
Regulation of monocyte chemoattractant protein 1 by cytokines and oxygen free radicals in rat hepatic fat-storing cells.
Interleukin-8 (IL-8) and monocyte chemoattractant protein (MCP-1) are among the small proteins, termed chemokines, produced by immune system cells in response to microbial infections, especially viral infections.
To clarify the immune responses mediated by ficolins in the placenta during preeclamptic pregnancy, we found that chemokines/cytokines involved in innate immunity, including monocyte chemoattractant proteins 1/2/3 (MCP1/2/3), monokine induced by gamma-interferon (MIG), macrophage inflammatory proteins 1[delta]/3[alpha] (MIP1[delta]/3[alpha]), tumor necrosis factor [alpha] (TNF[alpha]) and thymus expressed chemokine (TECK) were activated, whereas interferon/cytokines involved in adaptive immunity, including interferon [gamma] (IFN[gamma]), interleukin 13/4/5 (IL13/4/5), transforming growth factor [beta]1/[beta]3 (TGF[beta]1/[beta]3) and TNF[beta], were suppressed in preeclamptic placenta (n = 10 vs 10; Fig.
The market scenario will change following the launch of new disease modifying therapies such as ACEs inhibitor, antioxidant inflammation modulator, connective tissue growth factor (CTGF) Inhibitor, monocyte chemoattractant proteins (MCP) inhibitor, selective glycation inhibitor, transforming growth factor beta regulator, selective Endothelin-A Receptor (ETAR) antagonist, urotensin II receptor antagonist, IL-12 inhibitors and STAT-4 activator, Nox4 inhibitor, G protein-coupled receptors (GPCRs) antagonist, and erythropoiesis stimulating agent.
CCR2 receptors are found on the surface of monocytes, macrophages and T-cells and bind hormone-like "chemokines" known as monocyte chemoattractant proteins (MCPs).
The CCR2 receptor is found on the surface of monocytes and some T cells and binds hormone-like "chemokines" known as monocyte chemoattractant proteins (MCPs).

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