methaqualone

methaqualone

 [meth″ah-qua´lōn]

a nonbarbiturate compound formerly used as a sedative and hypnotic; now found only as a drug of abuse. See drug abuse.

methaqualone

(mĕth′ə-kwā′lōn′)

n.

A potentially habit-forming drug, C₁₆H₁₄N₂O, formerly used as a sedative and hypnotic.

methaqualone

An addictive Schedule-II hypnotic-sedative quinazolone with barbiturate-like effects which, when it was legal, was used to reduce anxiety and tension. It was a popular drug of abuse, and it was linked to physical or psychologic dependence.

Clinical findings
Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anaemia.
 
Route
Oral, injected, sniffed, smoked.
 
Management of overdose
Haemoperfusion.

Toxic range
> 8 µg/mL, serum; > 300 µg/L, urine.
 
T1/2
20–60 hours.
 
Specimen
Serum, random urine.
 
Method
GC.

methaqualone

Quaalude, 'ludes' Substance abuse An addictive Schedule II hypnotic-sedative quinazolone with barbiturate-like effects; methaqualone was a popular drug of abuse and linked to physical or psychologic dependence Clinical Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anemia Route Oral, injected, sniffed, smoked Used for Anxiety, tension Management Hemoperfusion. See Controlled drug substance.