methaqualone
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methaqualone
[meth″ah-qua´lōn]methaqualone
(mĕth′ə-kwā′lōn′)n.
A potentially habit-forming drug, C16H14N2O, formerly used as a sedative and hypnotic.
methaqualone
An addictive Schedule-II hypnotic-sedative quinazolone with barbiturate-like effects which, when it was legal, was used to reduce anxiety and tension. It was a popular drug of abuse, and it was linked to physical or psychologic dependence.Clinical findings
Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anaemia.
Route
Oral, injected, sniffed, smoked.
Management of overdose
Haemoperfusion.
Toxic range
> 8 µg/mL, serum; > 300 µg/L, urine.
T1/2
20–60 hours.
Specimen
Serum, random urine.
Method
GC.
methaqualone
Quaalude, 'ludes' Substance abuse An addictive Schedule II hypnotic-sedative quinazolone with barbiturate-like effects; methaqualone was a popular drug of abuse and linked to physical or psychologic dependence Clinical Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anemia Route Oral, injected, sniffed, smoked Used for Anxiety, tension Management Hemoperfusion. See Controlled drug substance.methaqualone
a nonbarbiturate hypnotic similar to barbiturates in its effects.