moesin


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moesin

A protein that belongs to the ERM (that is, ezrin, radixin, and moesin) group of the band 4.1 superfamily of proteins that assist in the establishment of submembrane cytoskeletal scaffolds to maintain membrane architecture and functional capacity. Moesin is required for the accurate organization of the cytoskeletal component of the apical membranes.

moesin

Membrane-organising extension spike protein. A protein encoded by MSN on chromosome Xq11.1 which is localised to filopodia and other membranous protrusions that are important for cell–cell recognition, signalling and cell movement.
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Tumor suppressive microRNA-133a regulates novel targets: moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.
E-Cadherin, zyxin, and moesin were identified as genes differentially expressed in these clusters.
The protein kinase A-anchoring protein moesin is bound to pigment granules in melanophores.
1); amino-terminus of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase gene (ATIC, 2q35); TRK-fused gene (TFG, 3q21), with 3 variants depending on the length (short, long, extra-long); clathrin heavy polypeptide gene (CLTC, 17q23); moesin gene (MSN, Xq11-12); myosin heavy chain 9 gene (MYH9, 22q11.
The immunophenotype of basal-like tumors, as defined by GEP or by IHC surrogate markers, is characterized by positive expression of basal CKs, EGFR, p53, P-cadherin, caveolins 1 and 2, cyclin E, Ki-67, c-Kit, fascin, Sox2, moesin, vimentin, nestin, and laminin (Figure 2).
Some actin assembly-regulating proteins (thymosins, moesin, Arp 2/3) were also up-regulated, while muscle contractile proteins were either up-regulated ([alpha]-cardiac myosin heavy chain, atrial myosin light chain 1) or down-regulated (titin, tropomyosin 4, troponin I, etc).