MAP3K13

(redirected from Mlk)
Also found in: Acronyms, Encyclopedia.

MAP3K13

An oncogene on chromosome 3q27 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K13 activates the JUN N-terminal pathway by activating the MAP kinase kinase MAP2K7. It acts synergistically with PRDX3 to regulate kinase-dependent NF-kappaB activation in the cytosol, which involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappaB.

Each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of three protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which in turn activates a specific MAPK.
References in periodicals archive ?
The History Channel's Twitter account was posting about MLK today, even sharing a Washington Post article about him, but the network still has nothing on the schedule.
Today at MLK, I find that some of the older books still exude the familiar library perfume--that dark smell, like whiskey made from fallen leaves.
Average weekend drops for holiday openers (since 2000) (in millions of $) Weekend 1 (four-day) Weekend 2 (three-day) MLK Day $16 8 -53% Presidents' Day 18 9 -52% Memorial Day 48 19 -62% Labor Day 9 3 -63% Note: Table made from bar graph.
Most are excerpts taken from the larger works: for instance, from Parting the Waters, the prize-winning biography of MLK by Taylor Branch, is a description of King speaking about "the bus situation in Montgomery" to people gathered in a church after the Rosa Parks has been arrested.
The idea is to use the MLK Day holiday as a "day on"--a day of action--instead of a day off.
Black history is at the Ralph Mark Gilbert Civil Rights Museum (460 MLK Blvd.
a day-long celebration at the MLK Library was televised by a local station.
Several facts about the MLK holiday attract scholars of minority politics and compel a formal treatment in the mainstream literature.
A more serious problem involves the form mlk in lines 4-5; both mlk `king' (lines 1, 10-11, 18, 23) and mlk `to reign' are found (the latter in line 2, by.
The event also features performances by Aurora students, honors for those participating in the annual MLK Day of Service and recognition for student leaders with the mayor's Service Above Self Awards.
Tenders are invited for Purchase of ArcGIS Master Lab Kit(MLK) Additional Lab Kit (qty 1) consisting of 3 desktop users, compatible to the upgraded license of previous ArcGIS MLK, consisting of all features to be identical toexisting set and with minimum 1-year warranty.