mal de Meleda

(redirected from Mljet disease)

mal

 [mal] (Fr. and Sp.)
mal de Meleda symmetrical keratosis of the palms and soles associated with a dry, scaly thickening of the wrists and ankles.
mal de mer seasickness.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mal de Me·le·da

[MIM*248300]
endemic symmetrical keratoderma of the extremities occurring on the island of Meleda off the coast of Dalmatia, in Eastern Europe.
Farlex Partner Medical Dictionary © Farlex 2012

mal de Meleda

An autosomal recessive condition (OMIM:248300) causing symmetric palmoplantar hyperkeratosis and acanthosis, with circumscribed hyperkeratosis of wrists, knees, forearms, ankles, brachydactyly, koilonychia, growth and mental retardation, seen in the endogamous population of the island of Meleda off the coast of Dalmatia in former Yugoslavia.
 
Molecular pathology
Mal de Meleda is caused by a mutation of SLURP1 on chromosome 8q24.3.

Mal de Meleda

An autosomal recessive condition (OMIM:248300) causing symmetric palmoplantar hyperkeratosis and acanthosis, with circumscribed hyperkeratosis of wrists, knees, forearms, ankles, brachydactyly, koilonychia, growth and mental retardation, seen in the endogamous population of the island of Meleda off the coast of Dalmatia in former Yugoslavia.
 
Molecular pathology
Mal de Meleda is caused by a mutation of SLURP1 on chromosome 8q24.3.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.