meprobamate

meprobamate

 [mĕ-pro´bah-māt, mep″ro-bam´āt]

an antianxiety agent and skeletal muscle relaxant; administered orally.

me·pro·ba·mate

(mĕ-prō'bă-māt mep'brō-bam'āt), Avoid the misspelling/mispronunciation meprobromate.

An oral anxiolytic with potential for dependency and addiction.

meprobamate

(mĕp′rō-băm′āt′, mĕ-prō′bə-)

n.

A bitter white powder, C₉H₁₈N₂O₄, used as a tranquilizer, muscle relaxant, and anticonvulsant.

meprobamate

A potentially addicting agent that blocks spinal interneurons, which has anticonvulsant, anxiolytic, muscle-relaxing, sedative, hypnotic and tranquilising properties.

Adverse effects
Hypotension, depression of brainstem activity, coma, death.
 
Metabolism
Liver; excreted in urine, stool.

Therapeutic range
5–30 µg/mL.
 
Toxic range
> 60 µg/mL.
 
Specimen
Serum.
 
Method
TLC, GC, colorimetry.

meprobamate

Pharmacology A potentially addicting agent with anticonvulsant, anxiolytic, muscle relaxing, sedative, hypnotic, tranquilizing properties that blocks spinal interneurons, depressing brainstem functions, coma, death; may cause hypotension Metabolism Liver; excreted in urine, stool. See Therapeutic drug monitoring.

me·pro·ba·mate

(mĕ-prō'bă-māt) Avoid the misspelling/mispronunciation meprobromate.

An oral anxiolytic with potential for dependency and addiction.

meprobamate

A mildly tranquillizing carbamate drug with muscle-relaxant properties used in combination with painkilling drugs to treat muscle and joint pain. A brand name is Equagesic.

me·pro·ba·mate

(mĕ-prō'bă-māt)

Oral anxiolytic with potential for dependency and addiction.