microsatellite

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Related to Microsatellite repeats: Simple Sequence Repeat

microsatellite

(mī′krō-săt′l-īt′)
n.
1. A short sequence of DNA consisting of multiple repetitions of a set of two to nine base pairs, used as a genetic marker when individuals differ in the number of repetitions.
2. A small artificial satellite, usually with a mass of less than 100 kilograms (220 pounds) when deployed in orbit.

microsatellite

A highly polymorphic segment of DNA composed of repetitive stretches of short sequences of 2–6 base pairs of DNA, which serve as genetic markers to track inheritance in families. Microsatellites include dinucleotides, trinucleotides and tetranucleotides, repeated in tandem arrays throughout a genome. The human genome has 50–100,000 microsatellite loci.

microsatellite

A section of DNA in which a unit of one to five nucleotides is repeated a variable number of times. Repeating trinucleotides that expand during meiosis are associated with Huntington's disease and fragile X syndrome.
References in periodicals archive ?
On an evolutionary timescale, the changes in the number of microsatellite repeats are rare.
The microsatellite repeats used as probes for fuorescence in situ hybridizaton experiments have proved to be resolute markers in the analyzed species.
Genomic DNA was enriched for microsatellite repeats as described in Hamilton et al.
The computer program Vector NTI (InforMax, Inc., Frederick, MD) was used to remove vector sequence, remove redundant clones, and identify microsatellite repeats. Microsatellites were identified as motifs repeated at least five times.
If the prototypical cohanim Y chromosome arose fairly recently, then the number of microsatellite repeats should be relatively similar among all the cohanim.
The gp60 allele and subtype were identified by multiple sequence alignment with GenBank reference sequences and phylogenetic analysis that used ClustalX version 1.8 (www.clustal.org) as well as manual quantification of microsatellite repeats.
CpG suppression in vertebrate genomes does not account for the rarity of (CpG)n microsatellite repeats. Genomics 17:890-891.
For several years, gene mappers have used DNA signposts called microsatellite repeats as markers to delineate these sections.
However, among eukaryote species, microsatellite repeats are more abundant and longer in vertebrates than invertebrates (Chambers and MacAvoy 2000).
Of the 306 cloned inserts sequenced from di- and trinucleotide repeat microsatellite-enriched libraries, 250 (82%) were unique and contained microsatellite repeats. One hundred fifty-five (62%) clones had perfect repeats.
Microsatellite repeats in grapevine reveal DNA polymorphisms when analyzed as sequence-tagged sites (STSs).