microglia

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Related to Microglial cells: Astrocytes

microglia

 [mi-krog´le-ah]
non-neural cells forming part of the adventitial structure of the central nervous system. They are migratory and act as phagocytes of waste products of the nervous system. adj., adj microg´lial.

mi·crog·li·a

(mī-krog'lē-ă), This word is grammatically singular. Avoid the mispronunciation microgli'a.
Small neuroglial cells of the central nervous system, originating in the bone marrow, that may become phagocytic in areas of neural damage or inflammation.
[micro- + G. glia, glue]

microglia

/mi·crog·lia/ (mi-krog´le-ah) small nonneural cells forming part of the supporting structure of the central nervous system. They are migratory and act as phagocytes to waste products of nerve tissue.microg´lial
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Microglia.

microglia

(mī′krō-glē′ə, -glī′-)
n.
(used with a pl. verb) Any of the small neuroglial cells of the central nervous system having long processes and amoeboid and phagocytic activity at sites of neural damage or inflammation.

microglia

[mīkrog′lē·ə]
Etymology: Gk, mikros + glia, glue
small, migratory interstitial cells that form part of the central nervous system. They have various forms and slender, branched processes. Microglia serve as phagocytes that collect waste products of the nerve tissue of the body. Also called Hortega cells, mesoglia.
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Microglia

microglial cell

A perivascular bone-marrow-derived cell native to the CNS, belonging to the mononuclear phagocytic system (e.g., monocytes, macrophages, dendritic cells and granulocytes), which presents antigens in an MHC-class-II restricted context.

mi·crog·li·a

(mī-krog'lē-ă)
Small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation.
Synonym(s): Hortega cells.
[micro- + G. glia, glue]
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MICROGLIA

microglia

(mi-krog'le-a) [? + glia, glue]
Cells of the central nervous system (CNS) present between neurons or next to capillaries. These cells may function as macrophages when they migrate to damaged CNS tissue.
See: gitter cell; illustration

microglia

Neurological connective tissue MACROPHAGES. Compare MACROGLIA.

Hortega,

Pio del Rio, Spanish neurohistologist in South America, 1882-1945.
Hortega cells - small neuroglial cells that may become phagocytic in areas of neural damage or inflammation. Synonym(s): microglia
Hortega neuroglia stain - one of several silver carbonate methods to demonstrate astrocytes, oligodendroglia, and microglia.

microglia

non-neural cells forming part of the adventitial structure of the central nervous system. They are migratory and act as phagocytes of waste products of the nervous system.
References in periodicals archive ?
Peripheral lipopolysaccharide stimulation induces interleukin-1 beta messenger RNA in rat brain microglial cells.
Microglial cells form part of the supporting structure of the central nervous system.
Furthermore, reperfusion injury in the PIT model can damage microglial cells, leading to silenced neuroinflammation [58].
Microglial cells are the brain's first and primary immune defense.
The surrounding tissue was gliotic and contained a mixed inflammatory infiltrate including perivascular lymphocytes and plasma cells as well as microglial cells with loose microglial nodule formation (Figure 3).
Pro-inflammatory cytokines can penetrate the blood-brain barrier and affect those microglial cells located in specific areas of the brain involved in mood regulation and reward process.
Six weeks after transplantation, however, more bone marrow-derived microglial cells were observed in the olfactory bulbs of the test animals where the degeneration of mitral cells was still in progress.
Later on it was reported that minocycline was also effective in adjunct therapy for acquired immunodeficiency syndrome (AIDS) dementia by virtue of its anti-inflammatory effect on the microglial cells thereby inhibiting their activation and also inhibiting virus production from these cells (20).
But recent research indicates that luteolin improves cognitive health by acting directly on the microglial cells to reduce their production of inflammatory cytokines in the brain.
As part of the three-year project, which is funded by a grant from the Alzheimer's Research Trust, Emma will transform stem cells from patients into microglial cells - types of brain cell acting as the brain's immune system.
Microglial cells isolated and purified from the brains of Wistar rats were cultured in the laboratory and subjected to various experiments in which they were treated with the mushroom extracts at dosages varying from 50-400 ug/mL and exposed to lipopolysaccharide or cell membrane fractions treated with 1-methyl-4-phenylpyridinium (MPP+).
Our recent work has shown that thoracic SCI causes microglial cells to activate at multiple levels along the sensory neuraxis and to contribute to the maintenance, in real time, of hyperexcitability of dorsal horn and thalamic somatosensory neurons, which leads to chronic pain [10,12-13].