In patients with SSc, endothelial dysfunction may occur secondary to autoimmune complication and SRC-related microangiopathic
Surveillance for physician-diagnosed postdiarrheal hemolytic uremic syndrome, a complication of STEC infection characterized by renal failure, thrombocytopenia, and microangiopathic
anemia, is conducted through a network of nephrologists and infection preventionists and by hospital discharge data review.
Cardiac autonomic neuropathy in diabetic patients: influence of diabetes duration, obesity, and microangiopathic
complications--the French multicenter study.
In aTTP, the accumulation of ultra-large vWF causes extensive clot formation in small blood vessels throughout the body, leading to severe thrombocytopenia (very low platelet count), microangiopathic
hemolytic anemia (loss of red blood cells through destruction) and ischemia (restricted blood supply to parts of the body), disclosed the company.
 The major morbidities in type 2 diabetes are due to its microangiopathic
and macroangiopathic complications.
Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic
hemolytic anemia, thrombocytopenia, and organ dysfunction.
Central to the diagnosis of TMAs is thrombocytopenia, microangiopathic
hemolytic anemia (MAHA) and the clinical or histological effects of microvascular thrombosis.
Obesity may cause microangiopathic
changes associated with the inflammatory process (1,2).
HUS includes microangiopathic
hemolytic anemia, thrombocytopenia, and acute kidney injury.
These conditions include presence of: 1) reticulated and large/giant platelets as in Bernard-Soulier syndrome, Gray platelet syndrome, essential thrombocythemia and immune thrombocytopenia 2) fragments of white and red blood cells2 as in myelodysplastic syndromes and microangiopathic
haemolytic anaemias like disseminated intravascular coagulation and thrombotic thrombocytopenic purpura / Haemolytic uremic syndrome (TTP/HUS), 3) significant RBC microcytosis as in severe iron deficiency anaemia and thalassemia syndromes.3 Other interferences that may produce inaccurate platelet counts by impedance method include micro clots, blood parasites and reagent contamination.
Haemolytic uraemic syndrome is characterised by the onset of microangiopathic
anaemia (damaged erythrocytes), thrombocytopenia and may be accompanied in adults by thrombotic thrombocytopenic purpura (a diffuse formation of microangiopathic
thrombi, often with concurrent neurological abnormalities) (12, 44).