microarray

(redirected from Micro array)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Micro array: Microarray analysis, Protein microarray

microarray

(mī′krō-ə-rā′)
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

microarray

An array of hundreds or thousands of spots containing specific oligonucleotides, cDNAs, proteins, peptides or other small molecules chemically attached to a substrate and organised in a grid on a glass or plastic slide, silicon chip, fibre-optic array or filter membrane. The microarray is bathed with probes to analyse gene expression by hybridisation, and it is used to detect changes in gene expression by comparing radioactively or chemically labelled cDNA prepared from the total mRNA of an experimental sample to that of a control sample. The relative intensity of the signal corresponding to each spot in the microarray reveals whether the expression of a particular gene is increased, decreased or unchanged.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

microarray

A collection on a chip of thousands of biological probes such as DNA single-strand sequences, protein-detecting molecules, or any other biologically-identifying material, that can be used to survey a specimen for the presence of a target gene or substance. Binding to the target substance can be made to cause fluorescence to occur at the unique spot or spots on the array and the chip can then be read by a scanner and the result displayed on a computer monitor. See also DNA MICROARRAYS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

microarray

see DNA MICROARRAY.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Santa Paula, CA, August 04, 2017 --(PR.com)-- Abrisa Technologies is pleased to announce that it can now supply Asahi Glass Corporation (AGC) EN-A1 Alkali Free Boro-Aluminosilicate glass for applications such as sensitive bio-photo detection, high throughput sensors, image sensor windows, biosensors, enhancement glass for thin displays, cover glass for micro arrays, and for low weight, reduced profile designs.
Already microfluidics has played a role in the development of DNA micro arrays used for diagnostic and drug discovery applications, micro-propulsion and micro-thermal technologies, and lab-on-a-chip systems.
Vegrandis develops, builds and sells micro arrays and laboratories-on-a-chip for clinical diagnostics, drug discovery, environmental monitoring and other applications, the company said.
Traditionally, instrumentation for positioning slides, test tube and micro arrays has depended on lead screw mechanisms.

Full browser ?