microRNA

(redirected from Micro RNA)
Also found in: Dictionary.
Related to Micro RNA: Microarray

microRNA

(mī′krō-är′ĕn′ā′)
n. Abbr. miRNA
Any of various short, single-stranded RNA molecules that regulate gene expression by binding to messenger RNA molecules, usually in untranslated regions.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

microRNA

Any of a group of short (generally 21 to 24 nucleotides in length), non-coding RNA molecules which fold upon themselves (“hairpins”) and are usually cleaved from larger hairpin-containing RNA (itself often processed from some portion of mRNA).

MiRNA is conserved through evolution and plays a role in RNA interference, destroying mRNA made by specific genes, suppressing gene expression and controlling translation of target mRNAs, thereby regulating critical aspects of plant and animal development.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

microRNA

(mī′krō-ăr′ĕn″ā″) [″ + ″],

miRNA

Oligonucleotides that prevent a variety of messenger RNAs from being transcribed from DNA or translated into proteins. They typically consist of 21 to 25 linked nucleotides.
Medical Dictionary, © 2009 Farlex and Partners

microRNA

Very short segments of RNA involved in RNA INTERFERENCE and recently shown to be important elements in the development of plant structure. Many genes that code for microRNA have been found in many species including H. sapiens . There is much current speculation into their role in human development.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
The exciting breakthrough suggests the microscopic messengers - micro RNAs - could act as a safe and effective new treatment.
We will continue to investigate this micro RNA as an inhibitor of ovarian cancer metastasis," says pathologist Wei Zhang, senior author of the paper appearing in Cancer Cell.
[3] Nonstandard abbreviations: BMA, Bone marrow aspiration; HSCT, hematopoietic stem cell transplantation; HPC, hematopoietic precursor cells; PB, peripheral blood; EMV, exosomes and microvesicles; mRNA, messenger RNA; miRNA, micro RNA; RT-PCR, reverse transcription PCR; SEM, scanning electron microscopy; Ct, cycle threshold; CBC, complete blood count; WBC, white blood cell; CR, complete remission; NH, normal hematopoiesis; RBC, red blood cells.
MCT-485 is a noncoding double stranded micro RNA (miRNA) which has demonstrated oncolytic and immune stimulating activity in in vitro models of hepatocellular carcinoma.
Gene regulation technologies, including micro RNA and RNA interference technology, is another segment of the market that holds great potential and is expected to achieve CAGR of over 15% from 2013 to 2019, the paper further reads.
"Targeted micro RNA expression in dairy cattle directs production of beta-lactoglobulin-free, high casein milk." PNAS published online 1 October 2012.
LC Sciences offers discovery, profiling and validation services for micro RNA, other small RNAs, whole transcriptome and mRNA expression analysis.
Micro RNA biogenesis: coordinated cropping and dicing.
miR-155 gene: A typical multifunctional micro RNA. Biochimica et Biophysica Acta (BBA) 2009;1792(6):497-505.
An important aspect highlighted and reviewed is that both genetic and the epigenetic effects of environment (through DNA methylation, histone modification and micro RNA) are passed down to the progeny and future generations forming the underlying cause for the burden of many chronic debilitating diseases seen in the offspring.
Murchison and her team analyzed patterns of gene and micro RNA activity in facial tumors and in healthy tissue.
CombiMatrix used a comprehensive micro RNA (miRNA, a recently discovered type of nucleic acid) array built on its CustomArray(tm) platform to perform this study.