Mg11 | definition of Mg11 by Medical dictionary
SAMHD1 (redirected from Mg11)
SAMHD1 A gene on chromosome 20pter-q12 that encodes a putative nuclease involved in the innate immune response, which acts by downregulating cell-intrinsic antiviral response. It may play a role in mediating pro-inflammatory responses to TNF-alpha signalling. It is expressed in the heart, skeletal muscle, spleen, liver and elsewhere, but not in the brain or thymus.
Defects in SAMHD1 cause Aicardi-Goutieres syndrome type 5 and chilblain lupus type 2.
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References in periodicals archive
Further studies have shown that these modifications are unfortunately accompanied by low metabolic stability predominantly for MG11 [7,8].
Hereafter cells were incubated in triplicate with increasing concentrations [0.001-1.000 nM] of competitor solution (50 [micro]L of metal-bound ([[sup.nat]Ga]) mono-, di-, and trimer as well as DOTA- MG11 as reference diluted in 20 mM HEPES, 10 mM Mg[Cl.sub.2] and 0.1% BSA).
Is there any serving officer able to send me a blank MG11
(witness statement)?" Jim then wrote: "I agree with handing it to the next [inquiry] chairperson but I also think we should hand a copy to the Commissioner."
Unpublished alphabetical, numerical and geographical list of Manitoba automobile owners and chauffeurs from 1907 to 1910, based on a typescript in the Provincial Archives of Manitoba (MG11