lipoid theory of narcosis

(redirected from Meyer-Overton theory of narcosis)

lip·oid the·o·ry of nar·co·sis

that narcotic efficiency parallels the coefficient of partition between oil and water, and that lipoids in the cell and on the cell membrane absorb the drug because of this affinity.
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lip·oid the·o·ry of nar·co·sis

(lip'oyd thē'ŏr-ē nahr-kō'sis)
That narcotic efficiency parallels the coefficient of partition between oil and water, and that lipoids in the cell and on the cell membrane absorb the drug because of this affinity.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Meyer,

Hans H., German pharmacologist, 1853-1939.
Meyer-Overton rule - because inhalation agents act through the central nervous system cells, anesthetic potency increases with lipid solubility.
Meyer-Overton theory of narcosis - that narcotic efficiency parallels the coefficient of partition between oil and water, and that lipoids in the cell and on the cell membrane absorb the drug because of this affinity. Synonym(s): lipoid theory of narcosis
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