The observation of the infants was done before and during the methylxanthine
treatment, with the help of a cardio respiratory monitor and a pulse oximeter.
Early investigations have shown that some methylxanthines
(caffeine, pentoxifylline, and others) at concentrations of an order of ca.
Almost half the individuals were receiving methylxanthines
, representing most of the patients who received only one controller medication.
Due to its methylxanthine
content, mate is a proven energizer.
Since then, other researchers reporting on much larger groups of women have reported "no evidence of an association between methylxanthine
consumption and benign breast disease." Of course, if a woman with fibrocystic breast disease feels better without coffee, she should by all means stay away from it.
Theophylline is the major methylxanthine
used in asthma therapy.
0.25 mM IBMX (3-isobutyl-1 methylxanthine
; Sigma-Aldrich, Saint Louis, MO, USA) was added to the adipogenic differentiation cultures upon first change of culture media.
Seizures worsened with phenobarbital partially inhibiting GLUT 1, diazepam, methylxanthine
and caffeine (9).
 Since 1970s, methylxanthine
derivatives have been administered both parenterally and orally to decrease the frequency of apneic episodes and prevent the need for assisted ventilation.
Second, studies are needed to measure changes in catecholamine or methylxanthine
concentrations in response to acute caffeine intake.
For that reason, it has been my practice to reserve high-dose iodine therapy for women who do not respond to more conservative measures such as methylxanthine
avoidance and supplementation with vitamin E.
In addition, restriction was imposed on the intake of methylxanthine
containing beverages, as well as on the consumption of grapefruit juice.