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An intermediate in the degradation of l-tryptophan and serotonin.
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For example, early exposure to the serotonin agonist, 5- methoxytryptamine, results in structural alterations in cortical column development and behaviors that include decreased social bonding, sensory-hyper-responsiveness, seizures and motor changes (Whitaker-Azmitia).
Symptoms reduction after one week of sertraline treatment was associated with the reduction of 5- methoxytryptamine levels, while it was associated with lower levels of branched chain amino acids at four weeks of sertraline treatment.