ADAM1cca22
(redirected from Metalloproteinase-Disintegrin ADAM22-3)ADAM1cca22
An ADAMs family protein encoded by ADAM22 on 7q21 which, unlike the other ADAMs, has no metalloprotease activity because it lacks a zinc-binding motif. ADAM22 is highly expressed in the brain, where it might function as an integrin ligand. ADAM22 is essential for correct myelination in the peripheral nervous system of mice.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.