(2002) Role of Rpn11 metalloprotease
in deubiquitination and degradation by the 26S proteasome.
EDTA, a metalloprotease
inactivator, achieved a significantly higher (P = 0.003) reduction of the proteolytic activity in L.
Lottaz et al., "Metalloprotease
meprinfi in rat kidney: glomerular localization and differential expression in glomerulonephritis," PLoS ONE, vol.
fragilis (ETBF) secrete a proinflammatory metalloprotease
toxin and have been associated with diarrheal disease in both children and adults.
Uitto, "Interferon-y coordinately upregulates matrix metalloprotease
(MMP)-1 and MMP-3, but not tissue inhibitor of metalloproteases
(TIMP), expression in cultured keratinocytes," Journal of Investigative Dermatology, vol.
Ananthanarayanan et al., "Extracellular matrix-mediated membrane-type 1 matrix metalloprotease
expression in pancreatic ductal cells is regulated by transforming growth factor-[beta]1," Cancer Research, vol.
A disintegrin and metalloprotease
17 (ADAM17), a ubiquitous sheddase formerly known as TACE (Figure 2), that releases a broad spectrum of soluble biologically active ligands from airway epithelial and myeloid cells is recognized as an important transducer of airway epithelial cis- and trans-signaling .
These activities were inhibited with the addition of a metalloprotease
inhibitor, 1,10-phenantroline, suggesting the participation of B.
These studies confirmed that the protease of this study was a [Zn.sup.2+] activated metalloprotease
The results revealed that 37 canonical pathways were enriched within the 99 genes upregulated in diabetic group and subsequently downregulated after HXJD treatment, including the role of macrophages, fibroblasts, and endothelial cells in rheumatoid arthritis, matrix metalloprotease
inhibition, and IL-6 signalling.
The Anticancer Effect of NnV Is Mainly Associated with Metalloprotease
. To confirm the bioactive component of the anticancer effect of NnV, we performed a cytotoxicity test using tetracycline (a metalloprotease
Giglio, "Structural and functional characterization of neuwiedase, a nonhemorrhagic fibrin(ogen)olytic metalloprotease
from Bothrops neuwiedi snake venom," Archives of Biochemistry and Biophysics, vol.