The subsequent reaction of compound 2 with methanesulfonyl chloride (mesyl chloride) at 0 [degrees]C temperature on constant stirring for 5 hours afforded the key intermediate (6-bromo-2 -chloroquinolin-3-yl)methyl methanesulfonate (3) in good yield.
acetyl, mesyl, benzoyl, etc) play an important role as common denominator for various biological activities, which is also revealed by a number of our previous works [911].