Merkel cell tumor

Mer·kel cell tu·mor

a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.
Farlex Partner Medical Dictionary © Farlex 2012


Friedrich Sigmund, German anatomist and physiologist, 1845-1919.
Merkel cell tumor - a rare malignant cutaneous tumor. Synonym(s): primary neuroendocrine carcinoma of the skin; trabecular carcinoma
Merkel corpuscle - a specialized tactile sensory nerve ending in the epidermis. Synonym(s): Merkel tactile cell; Merkel tactile disk; tactile meniscus
Merkel tactile cell - Synonym(s): Merkel corpuscle
Merkel tactile disk - Synonym(s): Merkel corpuscle
Medical Eponyms © Farlex 2012
References in periodicals archive ?
The findings could help guide imaging and other surveillance of patients after they develop a primary Merkel cell tumor, he added.
Desmet, "A cutaneous APUDoma or Merkel cell tumor? A morphologically recognizable tumor with a biological and histological malignant aspect in contrast with its clinical behavior," Cancer, vol.
Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor. Hum Pathol.
A similar result of discordant LT and VP1 positive Merkel cell tumor samples has been reported (8).
Caption: Interface between Merkel cell tumor cells (orange) and host immune cells (yellow and red).
Dworkin, "F-18 FDG accumulation in an octreotide negative merkel cell tumor," Clinical Positron Imaging, vol.
Vulvar Merkel cell tumor with glandular and squamous differentiation.
Establishment and characterization of two Merkel cell tumor cultures.
This may integrate the use of a genetically modified chimeric antigen receptor T cell (CAR-T) therapy that targets the oncogenic Merkel cell polyomavirus (MCPyV) in both positive and negative MCPyV Merkel cell tumors [24].
Unusual types of skin cancer include Merkel cell tumors. Merkel cell carcinoma starts when cells in the skin called Merkel cells start to grow uncontrollably.
Merkel cell tumors are aggressive neoplasms that often metastasize and, despite therapy, the disease-related death rate is high.