Merkel cell tumor

Mer·kel cell tu·mor

a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.


Friedrich Sigmund, German anatomist and physiologist, 1845-1919.
Merkel cell tumor - a rare malignant cutaneous tumor. Synonym(s): primary neuroendocrine carcinoma of the skin; trabecular carcinoma
Merkel corpuscle - a specialized tactile sensory nerve ending in the epidermis. Synonym(s): Merkel tactile cell; Merkel tactile disk; tactile meniscus
Merkel tactile cell - Synonym(s): Merkel corpuscle
Merkel tactile disk - Synonym(s): Merkel corpuscle

Merkel cell, Merkel disk

found in the basal layer of the epidermis; believed to act as slow-acting tactile endorgans.

Merkel cell tumor
see neuroendocrine cell tumor.
References in periodicals archive ?
The findings could help guide imaging and other surveillance of patients after they develop a primary Merkel cell tumor, he added.
Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor.
A similar result of discordant LT and VP1 positive Merkel cell tumor samples has been reported (8).
MCPyV was reported in 2008 and was identified in Merkel cell tumors, a rare form of skin cancer (8).
Caption: Interface between Merkel cell tumor cells (orange) and host immune cells (yellow and red).
Metastatic Merkel cell tumor to the prostate and bladder.
Vulvar Merkel cell tumor with glandular and squamous differentiation.
Establishment and characterization of two Merkel cell tumor cultures.
Unusual types of skin cancer include Merkel cell tumors.
Merkel cell tumors behave so aggressively in transplant patients that it's probably a poor idea to offer transplantation to anyone with a history of this form of cancer, he added.