MATH domain

(redirected from Meprin and TRAF homology domain)

MATH domain

A conserved 180-amino acid region shared by the functionally unrelated extracellular meprins A and B and the intracellular TNF receptor associated factor—TRAF proteins. The MATH domain appears to play a role in oligomerisation which is critical for establishing connections to form signalling complexes with TNF receptor-1.