ST14(redirected from Membrane-type serine protease 1)
ST14A gene on chromosome 11q24-q25 that encodes matriptase, a type-II transmembrane serine protease which degrades extracellular matrix and is thought to play a role in breast cancer invasion and metastasis.
Defects in ST14 cause ichthyosis with hypotrichosis, autosomal recessive.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.