GPBAR1(redirected from Membrane-type receptor for bile acids)
GPBAR1A gene on chromosome 2q35 that encodes a G protein-coupled receptor for bile acid. Bile acid binding induces GPBAR1 internalisation, activation of extracellular signal-regulated kinase and intracellular cAMP production; it is believed to be involved in the suppression of macrophage functions by bile acids.
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