For nerve impulses to pass rapidly along axons, it is important that some types of membrane channels
be "covered up" by the myelin coating and other channels be left exposed to help electrical current pass through the membrane.
"In the auditory system, the charge in the scolopale space drives ions, or electrically charged atoms, through membrane channels
in the sensory endings that open briefly in response to activation by sounds.
Recently, however STIM1 (Stromal interaction molecule 1, an endoplasmic reticulum (ER) [Ca.sup.2+] sensor) has been identified to regulate [Ca.sup.2+] entry into cells by interacting with plasma membrane channels
that mediate SOCE (3).
Scientists are studying neurotoxins to understand the membrane channels
that facilitate the transmission of nerve signals.
The knocked-out gene encodes a protein called Kv1.3, which normally assembles into some of the membrane channels
that control the flow of potassium ions in and out of cells and thereby regulate how readily nerve cells respond to stimuli.
This suggests that hemolysis is the result of hydrophilic membrane channels
established in the plasma membrane of the target red blood cell by the hemolytic protein of the cuticular secretion.
that allow sodium and potassium to pass through are essential for the movement of these signals.
In further experiments, the authors showed that this burst of activity is triggered suddenly by an all-or-none influx of calcium through specialized membrane channels
that open in response to this excitatory input.