melanosome

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melanosome

 [mel´ah-no-sōm″]
any of the granules that contain melanin. The melanin is synthesized within melanocytes; then the melanosomes are transferred to keratinocytes.

mel·a·no·some

(mel'ă-nō-sōm'),
The generally oval pigment granule (0.2 by 0.6 mcm) produced by melanocytes.
Synonym(s): eumelanosome
[melano- + G. sōma, body]

melanosome

A large (500-nm) lysosome-related pigment-containing organelle, which provides tissues with colour and photoprotection. They are the site of synthesis, storage and transport of melanin pigments and are synthesised in skin melanocytes, in choroidal melanocytes and in retinal pigment epithelial cells in the eye of mammals.

mel·a·no·some

(mel'ă-nō-sōm)
The generally oval pigment granule (0.2 by 0.6 mcm) produced by melanocytes.
[melano- + G. sōma, body]
References in periodicals archive ?
Comparable to the in vivo situation and other in vitro models, these melanosomes are arranged as a protective cap over cell nuclei to prevent damage to genetic information (Kaidbey et al., 1979; Liu et al., 2007).
It prevents the RNA and DNA synthesis of melanocytes, breaks down melanosomes, and causes melanocyte necrosis.
In our laboratory, the morphology of the viscacha retinal melanosomes has been described [44].
Although unhealthy/dying melanosomes have been observed histologically, it is unknown if this cell death is the primary mode of pigment loss.
Pathological aggregation and uneven distribution of melanosomes play a role in hypopigmentation.
* Stage 3: Transfer of melanin-filled melanosomes to keratinocytes located in the epidermis.
(8,9) Many have suggested defective transfer of melanosomes from melanocytes to keratinocytes.
Melanin and Melanosomes: The hallmark biological feature in the people of colour is the amount and distribution of pigment melanin.
Pathogenically, CARP results from disordered keratinization of the epidermis and increased melanosomes within the stratum corneum.
Zinc is the most abundant trace metal present in the retina [5] and is found mainly in the retinal pigment epithelium (RPE) and photoreceptor layers as well as in organelles including Golgi apparatus, melanosomes, and lysosomes [6-8].
The presence of huge numbers of melanosomes in melanocytes and circling keratinocytes was observed in an electronic microscope.