meglumine antimonate

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meglumine antimonate

A drug used in treating leishmaniasis.
See also: meglumine
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Isoproterenol (Injection 1mg/ml), Labetalol (Injection 5mg/ml), Meglumine Antimoniate (Injection 30%), Mercaptopurine (Tablets 50mg), Miltefosine Solid (Oral Dosage Form 10mg and 50mg), Phenoxymethylpenicillin (Powder for Oral Liquid 250mg/5ml), Procaine Penicillin (Injection 1MIU and 3MIU).
However, the first-line treatment of CL is meglumine antimoniate, which is not produced locally.
Intralesional meglumine antimoniate (MA) is one of these treatments; nonetheless, high cost, low compliance, and systemic toxicity have restricted the use of all these treatments.
There are several treatment options available1,6 but meglumine antimoniate (Glucantime)6 is still the treatment of choice.
Historical series of patients with visceral leishmaniasis treated with meglumine antimoniate in a hospital for tropical diseases, Maceio-AL, BRAZIL.
Objective: To compare the efficacy of combined intra-lesional meglumine antimoniate and cryotherapy versus cryotherapy alone for the treatment of cutaneous leishmaniasis in our population.
In vitro bir calismada MTT testi uygulanarak kalsiyum kanal blokoru olan verapamil ve meglumine antimoniate kombinasyonunun meglumine antimonate'a gore promastigot ve amastigotlar uzerine daha etkili oldugu gosterilmistir (39).
Recently, Azevedo and coworkers [17] evaluated the effect of a pegylated liposomal formulation of meglumine antimoniate (MA) on the pharmacokinetics and distribution of Sb in SWISS mice and in dogs.
The remaining dogs underwent treatment with a daily subcutaneous injection of meglumine antimoniate (80-100 mg/kg) for a month and allopurinol administered orally (10 mg/kg/12 hours) and were followed up for six months.
Meglumine antimoniate is the more common therapy for ATL in Latin America and amphotericin is the second choice drug.