megavitamin therapy

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The administration of supraphysiologic or in some cases ‘hyper-doses’—up to hundreds of times daily requirement—of vitamins, based on the belief that it will correct an unnamed disorder

megavitamin therapy

The administration of excess or 'hyper-doses' of water-soluble vitamins, either physician-guided–eg, to treat neuropathies, or self-prescribed by health-food advocates. See Decavitamin, Orthomolecular medicine, Vitamin.
Megavitamins, adverse effects  
Thiamin CNS hyperresponsiveness–convulsions, Parkinson's disease–thiamin antagonizes l-dopa, sensory neuropathy–destruction of dorsal axon roots
Niacin/nicotinic acid & niacinamide/nicotinamide Exacerbation of asthma–histamine release, cardiac disease–arrhythmias, GI symptoms, eg nausea, vomiting, diarrhea, anorexia, DM–hyperglycemia, gout–↑ uric acid, liver disease–enzyme leakage, hepatocellular injury, portal fibrosis or massive necrosis, cholestatic jaundice, peptic ulcer disease–histamine release, ↑ acidity, skin disease
Vitamin B6 Paresthesia, headaches, asthenia, irritability
Vitamin C ↑ Iron absorption, possibly iron overload, evoking diarrhea, renal calculus formation and possibly inhibiting the bacteriolytic activity of neutrophils, G6PD deficiency–↑ red cell lysis, megaloblastic anemia–↓ vitamin B12 absorption, nephrolithiasis–oxaluria Diagn Clin Testing 1990; 28:27  

meg·a·vi·ta·min ther·a·py

(meg'ā-vī'tă-min thār'ă-pē)
Large doses of vitamins, minerals, and amino acids that are used as medications to treat physical and psychiatric illnesses.
Synonym(s): orthomolecular medicine.
References in periodicals archive ?
Critics perceived that earlier reports on the effectiveness of megavitamins suffered from anecdotal reporting styles or glaring weaknesses in methodology (Hoffobin & Pueschel, 1982).
She took megavitamins and choline supplements, tried acupuncture, and cut down on gluten and dairy.
Claim: Offit claims that taking megavitamins (doses above RDA amounts) could increase the risk of cancer, heart disease, and mortality in "otherwise healthy" consumers.
A survey of 180 consecutive outpatients with diabetic neuropathy and other peripheral neuropathies found that the most frequently used CAM therapies were megavitamins (35%), magnetics (30%), acupuncture (30%), herbal remedies (22%), and chiropractic manipulation (21%).
Overall, 27.2% of the adolescents reported using herbal medicines, 26.7% reported using massage therapy, and 21.7% reported taking megavitamins (J.
In a survey of 1,038 women undergoing in vitro fertilization and oocyte retrieval, 33% reported having procedures such as acupuncture and relaxation therapy and 18% used herbal remedies, with megavitamins, echinacea, and primrose being the most popular, Dr.
Three-fourths of the article focused on secretin, and the remaining one-fourth discussed intravenous immunoglobulin and megavitamins.
(2) However, the growing presence of supplements on store shelves, including herbal remedies and megavitamins that tout benefits for memory and concentration, suggests an increase in their use.
Other popular modalities included dietary supplements, megavitamins, and spiritual practices, which were used by between 13% and 15% of respondents.
However, the megavitamin revolution that began in the 1930s presented a conceptual challenge to the medical community: megavitamins as drugs, now in competition with pharmaceuticals for the treatment of disease.
"The trend towards megavitamins can be dangerous when it comes to vitamin A," he said.
At the same time that I was being introduced to these natural approaches to treating cardiovascular disease, arthritis, cancer, and inflammatory disorders, I was also introduced to the use of megavitamins and diet for the treatment of mental disorders.