thrombopoietin

(redirected from Megakaryocyte Growth and Development Factor)
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thrombopoietin

 [throm″bo-poi´ĕ-tin]
a colony-stimulating factor that is the humoral regulator of the production of platelets.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

throm·bo·poi·e·tin

(throm'bō-poy'ĕ-tin), [MIM*600044]
A cytokine that serves as a humoral regulator for the production of blood platelets through action on the receptor c-mp1.
[thrombo- + G. poiētēs, maker, + in]
Farlex Partner Medical Dictionary © Farlex 2012

throm·bo·poi·e·tin

(throm'bō-poy'ĕ-tin)
A cytokine that serves as a humoral regulator for the production of blood platelets through action on the receptor c-mp1.
Synonym(s): megakaryocyte growth and development factor, megapoietin.
[thrombo- + G. poiētēs, maker, + in]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

thrombopoietin

A hormone responsible for the growth of colonies of megakaryocytes and the production of platelets. The existence of thrombopoietin has been suspected for 30 years but was realized only in 1994. In 1997 the results of a trial of polyethylene-conjugated genetically-engineered (recombinant) thrombopoietin-described as recombinant human megakatyocyte growth and development factor (PEGrHuMGDF)-was published. It was found to have a powerful stimulatory effect on PLATELET production. Thrombopoietin is the ligand for the cytokine receptor Mpl.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005