medicinal chemistry

(redirected from Medicinal chemist)

phar·ma·ceu·ti·cal chem·is·try

medicinal chemistry in its application to the analysis, development, preparation, and the manufacture of drugs.

medicinal chemistry

The discipline involved in discovering and developing new chemical compounds into useful medicines; the analysis, development, preparation, and manufacture of drugs.

Medicinal chemistry begins after biologically validated targets have been screened against a diverse library of compounds and promising initial chemical structures (known as hits) have been identified; the hits are then optimised to improve their therapeutic index—potency vs. toxicity.
References in periodicals archive ?
Dr Thomas is a medicinal chemist with more than 22 years in the pharmaceutical and biotech industry.
To access such information, the medicinal chemist typically walks up to one of several open-access systems configured for this purpose, submits a sample to the queue and selects a protocol HPLC/MS method.
As a medicinal chemist, I am absolutely full of opinions about any given list of chemical structures.
Medicinal chemist Dr Hoon L Tan said: "It is very exciting to find a compound in food that can target cancers specifically.
Dr Hoon L Tan, a medicinal chemist, said, "Salvestrols may offer a new mechanism of dietary anti-cancer action.
This is a fantastic breakthrough," said medicinal chemist Dr Hoon Tan.
Current MRI contrast agents "have no affinity for the cholesterol plaque," notes medicinal chemist David Cormode of the Mt.
10,000 will be awarded to an internationally recognized scientist, preferably a medicinal chemist, whose activities or published accounts have made an outstanding contribution to the practice of medicinal chemistry or to an outstanding example of new drug discovery.
This is not only important for discovery of potent Mcl-1 inhibitors but also opens up a broader opportunity to incorporate boronic acid warheads into TCIs to covalently inhibit a wider range of drug targets, says Qibin Su, Oncology Medicinal Chemist, IMED Biotech Unit.
Miller, a medicinal chemist and patent lawyer in the Boston area, and Evans, a scientist in the pharmaceutical business now working in regulatory affairs around Philadelphia, help chemists understand elements of patent law that could be important in their work.
Stout was Director of Medicinal Chemistry at Ricerca Biosciences and a medicinal chemist at Abbott Laboratories and American Critical Care.
Vennerstrom, a medicinal chemist at the University of Nebraska in Omaha.