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Dermatology Changes in the skin and subcutaneous tissues associated with growing older.  Ageing effects (e.g., patchy hyperpigmentation, fine wrinkles, telangiectasias) result from intrinsic and extrinsic processes and reflect the physicaleffects of the passage of time. Ageing skin is usually associated with a sagging face, in which deeper tissues (i.e., subjacent soft tissue) and structural landmarks lose their resiliency.
Geriatrics A multifaceted process in which bodily structures and functions undergo a negative deviation from the optimum. Ageing phenomena include decreases in memory, muscle strength, muscle mass, manual dexterity, cardiac output, and auditory and visual acuity, as well as loss or thinning of hair. Other ageing phenomena include increased body fat, and increased risk of cancer, diabetes, infections, osteoarthritis, and osteoporosis accompanied by a decrease in height due to decreased intervertebral space.

Intrinsic ageing The immutable effects of chronologic ageing, e.g., atrophy-attenuation of epidermis, retraction of rete pegs, decreased number of Langerhans’ cells and melanocytes, general decay of structural dermal and epidermal components
Extrinsic ageing Effects of external factors, e.g., sunlight, smoking, gravity and gravidity, keratinocytic dysplasia, solar elastosis, and possibly carcinogenesis; intrinsic & extrinsic ageing are intimately linked and thus not divided 
Ageing phenomena
Inevitable & immutable Cataracts, decreased skin elasticity, farsightedness, fibrous replacement of muscle, greying, poor recall, slowed intestinal transit, prostatic hypertrophy, wrinkling 
Inevitable but modifiable Baldness, cancer, reduced cardiac reserve, slow erection and ejaculation, decreased hearing, immunity, and vision, increased weight, liver spots (age spots), osteoporosis, decreased short-term memory, decreased stamina
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


The gradual accumulation of minor bodily injuries or degenerations often associated with a gradual decrease in functional capacity, that affects all human beings, to a greater or lesser degree, after middle age.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


the process of growing old or developing the characteristics associated with old age; the process involves increased susceptibility to age-related diseases and a decline in physiological vigour. It is known that there is a genetic basis to ageing and LONGEVITY in different organisms.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Patient discussion about ageing

Q. I would like to know the best age for pregnancy? Hi I am Deontae; I got married before 1 year. I and my wife planned to have a baby after 3 years. But now she is 25. I would like to know the best age for pregnancy? Which will help us to change our plan?

A. actually there is no best age for pregnancy (as far as i know), but some studies and research had shown that after 35 years old, a pregnancy is categorized as high risk, because there are some abnormalities and labor complication that are tend to happened (statistically) along with the increase of mother's age (such as: down syndrome, genetic disorder, post-partum bleeding, miscarriage, etc.)

so if your wife is now 25, i think you guys still have another 5-10 years to "accomplish" your family plan, hehehe...
Good luck, and stay healthy always..

Q. when is the most common age to get any kind of cancer? is there is such age?

A. no, not really. but i guess the older you get the older something can pop out. the cells are dividing and multiplying all of our life, and cancer can occur because of mutation happened in the cells.

Q. Does eyesight always decrease with age? I am 45 years old and never had glasses. All my friends are starting to wear reading glasses. Should I expect this too?

A. This is what usually happens; your eyesight deteriorates as you get older. Here is a link to a few things you can do in order to protect your eyesight:

More discussions about ageing
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References in periodicals archive ?
The median age for gastrodoudenal ulcers was 45 years which is in accordance to similar studies from India14,21.
The oldest place in the UK is West Somerset, with a median age of 55.0 in 2017.
Despite the decrease in median age in many of the Midwest's counties, a majority of counties in the country continued to grow older.
Out of 28 wards in Charnwood, four have a median age in the twenties, five in the thirties, 18 in the forties, and one in the fifties.
On average, the oldest people in Kirklees live in Holme Valley South, which has a median age of 46.5 years old.
* The median age at separation was 36 for women and 38 for men.
The median age of live TV viewers to NBA regular-season telecasts moved to 42 in 2016, from 40 in 2000.
Among counties with a population of 1,000 or more, only two nationwide had a median age of 60 or older.
The hottest markets are seeing inventory movement slow down slightly as the median age increased by two days on average from June.
The median age of diagnosis of CHL in the private healthcare sector was found to be 3.01 years in children who were not screened at birth, and 1.25 years in those children who were screened at birth (Table 3).
While Fallon resumed his usual late-night dominance beginning with Colbert's second night, CBS is still thrilled with Colbert, who is drawing a younger, more advertiser-friendly audience than predecessor David Letterman (median age of the Colbert Report's audience was 42 last year, a full 18 years younger than Letterman's Late Show median age before he stepped down in May) and is embracing brands in a way that his predecessor never did: Colbert's opening show featured a witty integration with Sabra hummus.
Thirty-one (36.9%), with a median age of 46 years, were in the chronic phase (CP); 23 (27.4%) with a median age of 52 years were in blast crisis (BC); and 30 (35.7%) with a median age of 58 years were in the active phase (AP).