mechanism of action

(redirected from Mechanisms of action)
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mechanism of action

(1) The manner in which a therapeutic agent acts, which includes blocking of receptors, enzymes, stimulating hormone production, etc. 
(2) The physiologic or biochemical processes within the body that are affected by a drug’s action, producing a given response.

mechanism of action

The means by which a drug exerts its effects on cells or tissues. It may have specific binding sites, receptor activation, enzymatic activity, or solubility.
See also: mechanism
References in periodicals archive ?
The major goal of this PEA is to support research focused on the mechanisms of action by which the mammalian innate immune system responds to the food and waterborne protozoa from the NIAID Category B Priority Pathogens list.
Drug candidates arising from these projects could shorten the treatment time for patients with TB and, because of their novel mechanisms of action, treat patients who are resistant to conventional therapies.
Mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics.
Many toxicogenomics studies are providing expression data for toxicants that have known mechanisms of action, with the eventual goal of inferring mechanisms of action for novel compounds.
The goals of single molecule research are to observe the dynamic behavior of individual molecules, to explore heterogeneity among molecules, and to determine mechanisms of action.
To characterize estrogenic chemicals and their mechanisms of action, we established in vitro and cell culture assays that detect human estrogen receptor [Alpha] (hER[Alpha])-mediated estrogenicity.