a test for onchocerciasis using an oral test dose of diethylcarbamazine (50 or 100 mg), resulting in the appearance of an acute rash in 2-24 hours from death of microfilariae in the skin.
Synonym(s): Mazzotti reaction
Farlex Partner Medical Dictionary © Farlex 2012
Mazzotti reactionA severe, potentially life-threatening allergic response that occurs within seven days of treatment of microfilariasis with diethylcarbamazepine in patients with onchocerciasis. The reaction correlates with the intensity of infection.
Intense pruritic rash, fever, malaise, lymphadenopathy, eosinophilia, arthralgia, tachycardia, hypotension, oedema, abdominal pain.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Mazzotti,Luigi, Mexican parasitologist, 1900-1971.
Mazzotti reaction - Synonym(s): Mazzotti test
Mazzotti test - diagnostic test of onchocerciasis. Synonym(s): Mazzotti reaction
Medical Eponyms © Farlex 2012