Caputo et al., "A single nucleotide polymorphism in the
matrix metalloproteinase-3 promoter enhances breast cancer susceptibility," Clinical Cancer Research, vol.
Progesterone analogues similarly modulate endometrial matrix metalloproteinase-1 and
matrix metalloproteinase-3 and their inhibitor in a model for long-term contraceptive effects.
Knofler, "Expression, Regulation and Functional Characterization of
Matrix Metalloproteinase-3 of Human Trophoblast," Placenta, vol.
Son et al., "A novel intracellular role of
matrix metalloproteinase-3 during apoptosis of dopaminergic cells," Journal of Neurochemistry, vol.
Hepatitis B virus X protein promotes cell migration by inducing
matrix metalloproteinase-3. J Hepatol 2005; 42:520-527.
Clinical disease activity in ankylosing spondylitis patients BASDAI <4 (n=20) BASDAI [greater Median than or equal to]4 (n=20) Median
Matrix metalloproteinase-3 6.48 40.91 (ng/mL) Matrix metalloproteinase-9 5.35 5.94 (ng/mL) Tissue inhibitor of matrix 6.16 6.61 metalloproteinase-1 (ng/mL) Erythrocyte sedimentation 18 29 rate (mm/hr) C-reactive protein (mg/L) 5.5 7 P *
Matrix metalloproteinase-3 <0.05 (ng/mL) Matrix metalloproteinase-9 <0.05 (ng/mL) Tissue inhibitor of matrix <0.05 metalloproteinase-1 (ng/mL) Erythrocyte sedimentation <0.05 rate (mm/hr) C-reactive protein (mg/L) <0.05 * Mann-Whitney U Test.
Matrix metalloproteinase-3 (MMP-3) is a zinc-dependent proteolytic enzyme that is converted to active MMP-3 through autocleavage; the active form remodels the extracellular matrix complex (EMC) in the basal lamina which forms part of the BBB [10].
Osteopontin, a novel substrate for
matrix metalloproteinase-3 (stromelysin-1)and matrix metalloproteinase-7 (matrilysin).
Additionally, the cartilage degrading enzyme
matrix metalloproteinase-3 was also evaluated in synovial fluid from OA patients.
Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1,
matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes.
Lower serum concentration of
matrix metalloproteinase-3 (MMP-3) in the acute stage of myocardial infarction.
Godon et al., "Increased production of
matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 by inflamed mucosa in inflammatory bowel disease," Clinical and Experimental Immunology, vol.