, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.
Akiyama et al., "Matriptase
activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis," Cancer Science, vol.
Additional evidence for the current consensus of protease-protease inhibitor deregulation in macrophages from patients with COPD was provided by the fact that human patients with the most common a1-antitrypsin mutation have greater proteolytic activity partially due to higher expression levels of the membrane-bound serine protease matriptase
Jin, "Increasing EMMPRIN and matriptase
expression in hepatocellular carcinoma: tissue microarray analysis of immunohistochemical scores with clinicopathological parameters," Histopathology, vol.
IL-4/13 significantly increased, whereas IFN-a significantly decreased the expression of kallikreins 5 and 7, matriptase
and channel-activating serine protease 1.
Cell surface proteolysis is an important process in development and maintenance of healthy epithelial homeostasis via proper functioning of type II transmembrane serine protease, matriptase
. The regulation of intestinal barrier integrity via matriptase
modulation is one of the key pillars in the normal gut physiology.
(100,115,117,118) Other proteases that have been shown to contribute to HNSCC invasion include MMP-10, (66) MMP-13, (80) matriptase
, (119) fibroblast activation protein, (120) and uPA/ uPAR, (117,121-124) as well as the glycosidase heparanase.
Fremont, CA, February 13, 2015 --(PR.com)-- AnaSpec is pleased to announce the launch of the first commercially available kit for measuring the activity of Matriptase
, a protease implicated in carcinogenesis.
Curcumin-targeting pericellular serine protease matriptase
role in suppression of prostate cancer cell invasion, tumor growth, and metastasis.
Co- localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase
. J Cell Physiol.
Purification and characterization of a complex containing matriptase
and a Kunitz-type serine protease inhibitor from human milk.
Curcumin treatment significantly resulted in reduced matrix metalloproteinase 9 activity and downregulation of cellular matriptase
, a membrane-anchored serine protease with oncogenic roles in tumor formation and invasion.