Mast cells


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Mast cells

A type of immune system cell that is found in the lining of the nasal passages and eyelids, displays a type of antibody called immunoglobulin type E (IgE) on its cell surface, and participates in the allergic response by releasing histamine from intracellular granules.
References in periodicals archive ?
These results could change the way everyday disorders such as asthma and the debilitating gastrointestinal symptoms of irritable bowel syndrome are treated by targeting mast cells.
Mast cells are present in every tissue of the body, but they are present in largest numbers in those tissues of the body that come into closest contact with the outside world.
Thus, mast cells can be used as an important indicator of the patient immunity in leprosy; as such these are found more in lepromatous than tuberculoid leprosy.
mast cells, eosinophils, macrophages) infiltrate shoulder sites of coronary plaques prior to an acute initial thrombotic event.
The growth factor stem cell factor, which stimulates mast cell development, was thought to be essential for the formation of mast cells.
Purified cells containing mast cells were harvested from the CNS and spleen, as described previously.
amp;nbsp;The researchers chose to study this specific drug because it targets a certain type of white blood cell, known as a mast cell, which drives inflammation in the lungs.
A survey of the number and distribution of mast cells in the skin of patients with mast cell disorders.
Cutaneous mast cell tumor is a common skin cancer of dogs, known by its highly variable biological behavior (GOLDSCHMIDT & HENDRICK, 2002; GROSS et al.
Mast cells are found in the skin and many tissues and lead to various clinical symptoms and signs by secreting many mediators when they are induced.
Patients typically experienced, at best, a nearly 60% drop in bone marrow mast cell burden and serum tryptase.
7] mast cells in 1mL RPMI1640 supplemented with 10% exosomes-free FBS and 10 ng rlL-4 for 72 h.