It is deemed that the single chromosome was included when the following structural aberration existed: chromosome/chromatide break, acentric fragment, ring fragment, minute, acentric ring, ring chromosome, marker chromosome
If a marker chromosome
is detected, microarray will identify it.
There were no clonal rearrangements except for the constant presence of a large marker chromosome
(denoted as mar1) that appeared as 1, 2, or 4 copies (Figure, h).
diversicolor supertexta karyotype can serve as a marker chromosome
pair, as they are subtelocentric (or telocentric in some metaphases) chromosomes and quite different from all chromosome pairs for H.
Molecular characterization of the marker chromosome
associated with cat eye syndrome.
It is likely that a complete genomic characterization of CLL requires a combination of fluorescence in situ hybridization (FISH), single nucleotide polymorphism (SNP) array profiling for comprehensive genome-wide analysis of acquired genomic copy number aberrations (aCNAs) and loss-of-heterozygosity (LOH) in dominant clones, and karyotyping for detection of balanced translocations, isochromosomes, and marker chromosomes
Many tumors are characterized by the presence of marker chromosomes
which are much altered as a consequence of multiple breaks (24).
whose origin cannot be identified by G banding are seen in hematological malignancies.
FISH also can be used to identify marker chromosomes
and to characterize rearrangements.
Fertility of the derived disomics and the presence of two of the marker chromosomes
involving the 4A[multiplied by]7B translocation, a typical evolutionary signature of durum wheat, further testified to the precise duplication of all chromosomes.
The rearrangements of chromosomes 1, 2, and 6 can be unambiguously identified and served as marker chromosomes
for the analysis of hybrids.