Marchiafava-Bignami syndrome

Marchiafava-Bignami disease

A condition that occurs in chronic alcoholics, clinically characterised by progressive neurological disease and histologically characterised by corpus callosum demyelination, necrosis and atrophy.

Marchiafava-Bignami syndrome

(măr″kē-ă-fă′vă-bē-nyă′mē)
[E. Marchiafava, It. pathologist, 1847–1935; A. Bignami, It. physician, 1862–1929]
Damage to the white matter of the brain, with dementia, resulting from chronic alcoholism, esp. excessive wine consumption.
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References in periodicals archive ?
(1) Besides these complications less common complications have been identified which includes Marchiafava-Bignami Syndrome, subacute encephalopathy with seizure activity (SESA Syndrome), alcohol cerebellar degeneration which are usually diagnosed by their characteristic MRI and EEG findings.
Study on alcohol and its neurological complications
Marchiafava-Bignami Syndrome. J Assoc Physicians India 2007;55:130
A rare case of: Marchiafava-Bignami disease

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